Thursday, April 18, 2019
Critical Analysison a study-Cancer cachexia- omega 3 benefits Essay
Critical Analysison a study-Cancer cachexia- omega 3 benefits - Essay Examplehe ability to assimilate nutrients for body-building is being compromised at the same time that the inherent disease is causing diminished appetite leading to poor feeding.Unlike primary protein energy malnutrition (which occurs in anorexia nervosa or kwashiorkor/marasmus), cachexia is induced by disease conditions. With primary protein energy malnutrition, the problem is one of shortsighted nutritional intake. But in cachexia, the issue is that patients, regardless of the adequacy of nutritional intake, pick up abnormally deepen disposition of nutrients, hence a negative balance of metabolism results (Fearon and Moses, 2002). Inflammatory processes are involved in secondary PEM which are absent in primary PEM, and while primary PEM can be change by reversal by bolstering nutrient intake, the same benefit cannot be obtained in secondary PEM. In primary PEM at that place is faster loss of adipose tissue than that of lean body mass, but the loss is equally from twain compartments in cachexia. Skeletal muscle loss is a feature that is peculiar to the cachexic state (Tisdale, 2003).Previous lab and clinical studies have shown that omega-3 fatty acids, especially eicosapentaenoic acid (EPA) and EPA-containing supplements demonstrate molecular anti-inflammatory action mechanism which is relevant to the attenuation of cachexia, in both humans and animal models. However, past results from multiple studies have been questionable in their findings, and this study aims to elicit independent objective evidence in favour of or against the suggest that EPA confers significant benefit in arresting the progress of cachexia in affected patients.Yes. There was lacking(predicate) discussion of the basis for their using the type of EPA preparations they used, as opposed to other available types. The authors could also have done a better job of reviewing the literature on the mechanistic aspects of how cachexia develops and what bearing this education will have on the approach they used for their
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